A purpose-built quarantine facility is set to be constructed at Jandakot Airport.
The Federal Government and State Government reached an agreement on Wednesday to bring a 1000-bed quarantine and emergency response facility to WA.
Under the agreement, the Commonwealth will fund the hub, estimated to cost around $400 million, and the WA Government will cover the day-to-day running costs.
The centre will accommodate returning overseas travellers during the COVID-19 pandemic and will have also have the capability to respond to future emergencies or natural disasters.
Premier Mark McGowan said he was pleased a formal agreement had been met to progress a purpose-built quarantine facility by the Commonwealth Government.
"WA has always stood ready to support the Commonwealth to deliver on its proposal for a dedicated quarantine facility to ensure more Australians can safely return to our shores following the devastating impacts of the global COVID-19 pandemic," Mr McGowan said.
"Over the past year and a half, we've had to introduce a range of measures, including hotel quarantine, to crush and kill the virus and to keep COVID out of WA.
"We look forward to this Commonwealth facility progressing as quickly as possible, to help keep WA safe."
The first 500 beds at the facility are expected to be ready by the end of March 2022.
Albanese announces $1.1 billion in road upgrades for Kwinana's Westport development
Drivers escape injury after head-on crash south of Perth
Whale carcass attracts sharks close to shore off Dawesville
Digital drivers' licences to be introduced in WA
Mandurah FIFO worker wins $250k
2026 ANZAC Day services across the Peel and Rockingham regions
Mother of 11-year-old boy killed in Mandurah scooter crash found safe and well
Peel charity desperately seeks funds to keep doors open
Australind train service set to resume